Uzm. Dr. Ertan Özen
GynaecologyVerified
- 36+years exp.
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Vaginal Rejuvenation
O-shot (genital prp)
What the O-Shot is, how platelet-rich plasma from your own blood is injected near the clitoris and front vaginal wall, what small studies show and what remains unproven for sexual function and urinary leakage, who it may suit, approximate costs in Turkey against the UK, US and Germany, recovery, risks and how to judge a clinic.
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Prof. Dr. Zehra Neşe Kavak
GynaecologyVerified
- 36+years exp.
English · Turkish
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What is the O-Shot (genital PRP) and how does it work?
The O-Shot (genital PRP) is a short outpatient treatment in which platelet-rich plasma (PRP) made from your own blood is injected into the tissue around the clitoris and the front wall of the vagina. A small amount of blood is taken from your arm, spun in a centrifuge to concentrate the platelets, and the resulting plasma is injected in small amounts after the area has been numbed. Platelets carry growth factors involved in tissue repair, so the idea is that they encourage blood flow, nerve sensitivity and tissue quality in the treated area. "O-Shot" is a brand name used by some providers; "genital PRP" describes the same basic technique.
The treatment is promoted for arousal, orgasm, vaginal dryness, discomfort with sex and mild stress urinary incontinence. This guide explains what the evidence says, who might consider it, what the O-Shot (genital PRP) costs in Turkey, what recovery is like and what risks to weigh. For the wider range of women's health care see our gynaecology treatments in Turkey.
Does the O-Shot actually work?
The honest answer is: possibly for some women, but the evidence is thin. The published studies are mostly small, short and often lack a control group. Some report improvements in self-rated desire, arousal, lubrication and orgasm over several months, and some report fewer leaks in mild stress incontinence. A few small randomised studies with a saline comparison have had mixed results, and sexual response is strongly influenced by expectation, relationship factors and hormones, which makes placebo effects hard to separate. Professional bodies such as the American College of Obstetricians and Gynecologists (ACOG) and the International Society for the Study of Women's Sexual Health have said that evidence for newer "vaginal rejuvenation" procedures does not yet support routine use. A trustworthy clinic will describe it as an experimental, optional treatment and will not promise a particular change in orgasm or desire.
What problems is it used for, and which are treated differently?
Women usually ask about the O-Shot for one of four reasons. Low arousal or difficulty reaching orgasm can be linked to hormones, medicines such as antidepressants, relationship or psychological factors, and pelvic floor tension; a doctor or sex therapist can assess these. Dryness and discomfort after menopause often respond to vaginal moisturisers and local oestrogen, which have solid evidence. Pain on penetration can come from several conditions that need a diagnosis first. Mild stress incontinence responds well to pelvic floor physiotherapy, and persistent leakage may need other procedures. PRP can be an add-on, but not a substitute for an assessment. If your main concern is tissue laxity or dryness, see our guides to vaginal rejuvenation with PRP and laser vaginal rejuvenation.
Who is and who is not a suitable candidate?
The treatment is meant for adult women who have talked through their symptoms with a doctor, have realistic expectations and understand that evidence is limited. You are less suited, or should wait, if you are pregnant or breastfeeding, have an active genital or urinary infection, an unexplained bleeding problem or suspected skin disease or cancer of the area, or a low platelet count or a blood disorder that makes PRP ineffective or risky. Some blood-thinning medicines and recent use of anti-inflammatory tablets such as ibuprofen can affect PRP and are usually paused beforehand on medical advice. Women with persistent pain should be examined first, because injecting into a painful area without a diagnosis can make matters worse.
O-Shot, laser, filler or exosomes: how do the options compare?
Several "intimate rejuvenation" treatments exist, and they are sold for overlapping reasons. The table gives a plain comparison; your own gynaecologist should say which, if any, fits your case.
| Option | Best suited to | Typical limits |
|---|---|---|
| O-Shot (genital PRP) | Interest in a minimal-downtime, own-blood treatment for sensitivity or mild leakage | Limited, mixed evidence; effect not assured |
| Vaginal laser | Dryness and mild laxity after menopause or childbirth | Regulators have warned that safety and effect are not established |
| Hyaluronic acid filler | Dryness, short-term volume or sensitivity | Temporary; allergic reactions and lumps possible |
| Exosome therapy | Tissue quality and dryness, where offered | Even less published evidence |
The wider topic is covered in our guide to vaginal rejuvenation. Local oestrogen, moisturisers and pelvic floor physiotherapy are low-cost options to try first for dryness and mild leakage.
How is the treatment done, step by step?
You first have a consultation with a gynaecologist, who takes a history and may examine you. On the treatment day, a nurse draws about 10 to 20 ml of blood, similar to a standard blood test. The blood is spun for around 10 minutes to separate the platelet-rich plasma. Meanwhile a numbing cream is applied, and sometimes a small local anaesthetic injection is added. The doctor then injects small amounts of PRP into the tissue beside the urethral opening, the front vaginal wall and around the clitoris, using a fine needle. Techniques differ between clinics, and some add a dermal roller or other products. The appointment lasts about 45 to 60 minutes, and the injection itself takes 10 to 15 minutes. The kit should be single-use and sterile.
O-Shot (genital PRP) cost in Turkey compared with the UK, US and Germany
The figures below are approximate ranges per session, not hospital quotes. The O-Shot (genital PRP) price depends on the PRP kit, the anaesthetic, any add-on products and whether a consultation is included. Prices outside Turkey are often higher because of clinic fees and the brand licence.
| Country | Approximate cost range |
|---|---|
| Turkey | €250 – €800 |
| United Kingdom | €600 – €1,600 |
| United States | €800 – €2,200 |
| Germany | €500 – €1,400 |
Some providers sell a course of two or three sessions. Ask whether the quote is for one treatment or a course, whether the consultation and any follow-up are included, and whether it is a branded kit or a standard PRP system. Ask for the price in writing.
What is recovery like after the O-Shot?
Recovery is short. Most women go back to normal activity the same day. You may feel mild soreness, swelling or a little spotting for a day or two, and bruising at the arm or injection sites is possible. Doctors usually advise avoiding sex, tampons, baths and swimming for 24 to 48 hours, and some advise waiting up to a week. Simple painkillers are normally enough, and anti-inflammatory tablets are often avoided for a few days because they can interfere with PRP.
Any effect is not immediate. Providers typically describe changes appearing over two to six weeks, with a maximum around three months, and some suggest repeating the treatment after several months. Because the treatment is quick, a stay of two to three nights is enough, including a consultation and a check. You can fly home the day after treatment if you feel well.
What results can I realistically expect?
There is no standard before-and-after photograph, because the aim is function and sensation, not appearance. Women in studies who report a benefit describe things like more lubrication, easier arousal or fewer leaks, and some notice nothing. It does not change the structure of the vagina, tighten a loose pelvic floor or treat pain from conditions such as vulvodynia or endometriosis. Hormonal, medical and emotional factors continue to play a large role in sexual satisfaction. A fair way to judge the treatment is to note your symptoms before, rate them on a simple scale each week for three months, and discuss the result with your own doctor.
What are the risks of genital PRP?
Because the plasma is your own blood, allergic reactions are unlikely, but there are still risks. These include pain, bruising, swelling, bleeding, infection at the injection site, a lump or irritation, and short-term numbness or pain with sex. Rare complications can come from poor technique, such as injury to the urethra or nearby tissue. Unsafe PRP practice has been linked to blood-borne infection in unregulated settings, which is why a single-use sterile kit and a licensed medical setting matter. Genital PRP is not a standard treatment in NHS or major gynaecology society guidance, and its long-term safety has not been studied in large trials. Discuss any chronic condition, blood disorder or medication with the doctor before treatment.
How to choose a clinic, and red flags
Choose a licensed hospital or clinic where a gynaecologist assesses you, explains that evidence is limited, uses single-use sterile PRP kits and gives you a written plan and price. Red flags include promises of a stronger orgasm or "rejuvenation", the claim that it replaces treatment of a medical problem, no examination, pressure to buy a course up front, unclear hygiene practice and no aftercare contact. Read how our process works and use our free quote page to ask a hospital to review your needs and send a written plan.
What should I ask the clinic before booking?
- Who performs the injection, and what are their qualifications?
- What evidence do you rely on, and what results do your patients usually see?
- Is the PRP kit single-use and sterile, and is it a branded system?
- Does the price cover the consultation, anaesthetic and a follow-up?
- Should I try local oestrogen or pelvic floor therapy first?
- Who do I contact if I have pain or bleeding after I return home?
Hospitals with Gynaecology in Turkey
Frequently asked questions
It is an injection of platelet-rich plasma made from your own blood into the tissue near the clitoris and the front vaginal wall. It is promoted for arousal, orgasm, dryness and mild urinary leakage, although the evidence is limited.
Some women report improved arousal, lubrication or fewer leaks, but studies are small and short, and placebo effects are hard to rule out. Professional societies say the evidence does not yet support routine use.
Approximate ranges are €250 to €800 per session in Turkey, against about €600 to €1,600 in the UK. Check whether the quote is for one session or a course and whether the consultation is included.
A numbing cream and sometimes local anaesthetic are used. Most women feel pressure or brief stinging during the injections, then mild soreness for a day or two.
Providers describe changes building over two to six weeks, with a peak at around three months. Some women notice no change, and no clinic can promise a specific result.
Most women return to normal activity the same day. Sex, tampons and baths are usually avoided for 24 to 48 hours, and mild soreness or spotting settles within a couple of days.
Using your own blood avoids allergy to the product, but infection, bruising and injury from poor technique are possible, and long-term safety data are limited. Choose a licensed clinic that uses single-use sterile kits.
Small studies suggest it may reduce mild stress leakage in some women, but pelvic floor physiotherapy has stronger evidence. A doctor should assess the cause of leakage first.
The O-Shot uses injected PRP from your own blood, while laser treatments use light energy on the vaginal lining. Both have limited evidence, and regulators have issued warnings about laser devices for this purpose.
The treatment takes less than an hour, so two to three nights including a consultation and a check is usually enough. You can usually fly home the day after if you feel well.
Patient stories